Accès rapides :

Vous êtes ici :

  1. Accueil
  2. Publications et outils
  3. Bases de données
  4. Fiches toxicologiques
  5. p-Phénylènediamine (FT 263) (rubrique sélectionnée)

p-Phénylènediamine

Fiche toxicologique n° 263

Sommaire de la fiche
Fiche complète (PDF 169,41 Ko) Fiche synthétique (PDF 73,75 Ko)
Nouvelle recherche

Édition : 2006

Bibliographie

  1. p-Phenylenediamine - Fiche n° 2124. In: Base de données Cheminfo. Hamilton, Centre Canadien d'Hygiène et de Sécurité, 2004.
  2. Phénylènediamine (para-) - Commission de la Santé et de la Sécurité du Travail, Répertoire toxicologique. Mise à jour 18/12/2000. Consultable sur le site www.reptox.csst.qc.ca/.
  3. WEISBURGER E. K., HUDSON V. W. - Aromatic nitro and amino com­pounds. In: Eula Bingham, Barbara Cohrssen, Charles H. Powell (ed.) - Patty's industrial hygiene and toxicology, 5e éd, John Wiley and sons, consultable sur CD-Rom, 2005.
  4. p-Phenylenediamine. Fiche Internationale de Sécurité Chimique n° 0805. Consultable sur le site www.cdc.gov/niosh. 1997.
  5. IUCLID Dataset. p-Phenylenediamine. 18 février 2000. European Commission. European Chemicals Bureau.
  6. KIRK-OTHMER - Encyclopedia of chemical technology, 4e éd., vol. 2. New York, John Wiley and sons, 1992, pp. 473-482.
  7. Phenylenediamines (1,2-Diaminobenzene, 1,3-Diaminobenzene, 1,4- Diaminobenzene). GDCh-Advisory Comittee on Existing Chemicals of Environmental Relevance, BUA report 97, 1994.
  8. OSHA Sampling and Analytical Methods, méthode n° 87, m-, o- and p- Phenylenediamine. OSHA Salt Lake City, 1991. Consultable sur le site www.osha.gov/.
  9. Health and Safety Executive - Methods for the determination of hazar­dous substances. Aromatic amines in air and on surfaces. MDHS 75. Consultable sur le site www.hse.gov.uk/pubns/mdhs/.
  10. p-Phenylenediamine. In: ACGIH - Threshold limit values for chemical sub­stances and physical agents and biological exposures indices, Cincinatti, 2001. Consultable sur CD-Rom.
  11. p-Phenylenediamine. In : IARC monographs on the evaluation of the car­cinogenic risks to humans, vol. 16, 1978 et suppl. 7, 1987.
  12. DRESSLER W. E., APPELQVIST T. - Plasma/blood pharmacokinetics and metabolism after dermal exposure to para-aminophenol or para-phenyle- nediamine. Food Chem Toxicol. 2006, 44: 371-9.
  13. GUARRIGUE J.-L. - In vitro genotoxicity of para-phenylenediamine ans its N-monoacetyl or N,N'-diacetylmetabolites. Mutation Research, 2006.

14.1,4-Benzenediamine, Complete Update 2005. In HSDB. Consultable sur le site toxnet.nlm.nih.gov/.

  1. HUEBER-BECKER F. et coll. - Human systemic exposure to a [14C]-para- phenylenediamine-containing oxidative hair dye and correlation with in vitro percutaneous absorption in human or pig skin. Food Chem Toxicol. 2004, 42: 1227-36.
  2. IMAIDA K. et coll. - Carcinogenicity and toxicity tests on p-phenylenedia- mine in F344 rats. Toxicol Lett., 1983, 16: 259-69.
  3. IOANNOU Y. M., MATTHEWS H. B. - p-Phenylenediamine dihydrochloride: comparative disposition in male and female rats and mice. J Toxicol Environ Health. 1985, 16: 299-313.
  4. KAWAKUBO Y. et coll. - N-Acetylation of paraphenylenediamine in human skin and keratinocytes. J Pharmacol Exp Ther. 2000, 292: 150-5.
  5. KRASTEVA M. et coll. - Dissociation of allergenic and immunogenic func­tions in contact sensitivity to para-phenylenediamine. Int Arch Allergy Immunol. 1993, 102: 200-4.
  6. LAUWERYS R.- Toxicologie industrielle et intoxications professionnelles, 4e ed. Masson, 1999.
  7. MATHUR A. K. et coll. - Biochemical and histopathological changes follo­wing dermal exposure to paraphenylene diamine in guinea pigs. J Appl Toxicol, 1990, 10, 383-6.
  8. MUNDAY R.- Mitochondrial oxidation of p-phenylenediamine derivatives in vitro: structure-activity relationships and correlation with myotoxic activity in vivo. Chem Biol Interact. 1992, 82: 165-79.
  9. NTP. Bioassay of p-Phenylenediamine dihydrochloride for possible carcino­genicity. US National Toxicology Program Technical Report Series n° 174, 1979.
  10. RE T. A. et coll. - The absence of teratogenic hazard potential of p-pheny- lenediamine in Sprague-Dawley rats. Fundam Appl Toxicol. 1981, 1: 421-5.
  11. SIEBEN S. et coll. - Delayed-type hypersensitivity reaction to paraphenyle­nediamine is mediated by 2 different pathways of antigen recognition by specificalphabetahuman T-cellclones. J Allergy Clin Immunol 2002, 109: 1005-11.
  12. STANLEY L. A. et coll. - Lack of evidence for metabolism of p-phenylene- diamine by human hepatic cytochrome P450 enzymes. Toxicology. 2005, 210: 147-57.
  13. STEILING W., KREUTZ J. and HOFER H.- Percutaneous penetration/dermal absorption of hair dyes in vitro. Toxicol In Vitro. 2001, 15: 565-70.
  14. WANG L. H., TSAI S. J. - Simultaneous determination of oxidative hair dye p-phenylenediamine and its metabolites in human and rabbit biological fluids. Anal Biochem. 2003, 312: 201-7.
  15. XIE Z. et coll. - Experimental study on skin sensitization potencies and cross-reactivities of hair-dye-related chemicals in guinea pigs. Contact Dermatitis. 2000, 42: 270-5.
  1. YABE K. - The effect of a p-phenylenediamine containing hair dye on the Ca2+ mobilization in the chemically skinned skeletal muscle of the rat. Nippon Hoigaku Zasshi. 1992, 46: 132-40.
  2. YAGI H. et coll. - Paraphenylenediamine induced optic atrophy following hair dye poisoning. Human and experimental Toxicology, 1996, 15, 617­618.
  3. GAUDEZ C. - Hypersensibilité cutanée retardée aux substances apparte­nant à la famille des paraphénylènediamines : contribution à l'étude de la capacité allergénique de ces substances utilisées dans la coiffure et l'indus­trie du caoutchouc. Thèse de médecine, université de Clermont-Ferrand 1, 2000.
  4. CRÉPY M.M. - Dermatoses professionnelles des coiffeurs. Fiche d'allergologie-dermatologie professionnelle TA 60. Doc Méd Trav, 2000, 81: 61­68.
  5. CRÉPY M.M. - Dermatoses professionnelles aux colorants. Fiche d'allergologie-dermatologie professionnelle TA 71. Doc Méd Trav, 2003, 100: 565­576.
  6. CRÉPY M. M. - Eczéma des paupières d'origine professionnelle. Doc Med Trav, 2003, n° 95, 365-371.
  7. SOSTED H. et coll. - Severe allergic hair dye reactions in 8 children. Contact Dermatitis. 2006, 54(2) : 87-91.
  8. KLINGMAN A.-M. - The identification of contact allergens by human assay. III. The maximization test: a procedure for screening and rating contact sensitizers. J. Invest. Dermatol. 1966, 47, 393-409.
  9. FUKUNAGA T. et coll. - Contact anaphylaxis due to para-phenylenedia- mine. Contact Dermatitis. 1996, 35: 185.
  10. BRANCACCIO R., COHEN D.E. - Contact leukoderma secondary to para­phenylenediamine. Contact Dermatitis. 1995, 32: 313.
  11. BAJAJ A.K. et coll. - Hair dye depigmentation. Contact Dermatitis. 1996, 35: 56.
  12. SHARMA V.K. et coll. - Para-phenylenediamine-induced lichenoid erup­tions. Contact Dermatitis. 1999, 41, 40-56.
  13. BROWN J.H. et coll. - Chronic renal failure associated with topical applica­tion of paraphenylenediamine. British Med. J. 1987, 294: 155.
  14. ROSENBERG N. - Allergie respiratoire des coiffeurs. Fiche d'allergologie- pneumologie professionnelle TR 30. Doc Méd Trav, 2002, 92: 417-425.
  15. Cuves et réservoirs - Recommandation CNAM R 276. INRS.
Nouvelle recherche
EN SAVOIR PLUS SUR LES FICHES TOXICOLOGIQUES